Can-C (N.A.C.) Eye Drops Ingredients
Can-C NAC Eye Drops (Previously Rre-Vital Eyes NAC Drops) is the original, high purity, tested, and approved brand. If you want assurances about what will work and what will be safe in your eye to use for months at a time, insist on Can-C Eyes Eye Drops. N-Acetyl Carnosine drops for lubrication of the eyes and used as part of the control of cataracts.
Cataracts are caused by the hardening and discoloration of the lens due to lifelong cross-linking (glycosylation) of the lens proteins with ascorbate. This persists in the aqueous humor at high concentrations, due to the low availability of natural defences in the form of antioxidants (which decline with advancing age).
N-acetylcarnosine delivers L-carnosine into the aqueous humor of the eye (the fluid area surrounding the lens) where it acts as a natural and comprehensive antioxidant, protecting structural lens proteins from the free-radical induced oxidation process.
As cataracts develops, antioxidant defence in the body is exhausted, leading to the cross-linking of the lens crystallins and producing a clouded lens and impaired eyesight. The clinical trials show that the regular use of a 1% N-acetylcarnosine (N.A.C.) eye-drop, delivers a high dose of carnosine capable of reversing the lens cross-linking of the lens crystallins and aids in the reduction and possible eradication of cataracts.
What is N-Acetyl-Carnosine (NAC)?
N-Acetyl-Carnosine (NAC) is a naturally occurring compound with a molecular structure identical to carnosine.
Carnosine and metabolic derivatives of carnosine, including NAC, are found in a variety of tissues but particularly muscle tissue. These compounds have varying degrees of activity as free radical scavengers.
NAC is particularly active against lipid peroxidation in the different parts of the lens in the eye. Hence why it is so essential to have as an active ingredient of eye drops used in order to prevent or treat cataracts.
During early experiments performed at the Moscow Helmholtz Research Institute for Eye Diseases, it was shown that NAC (1% concentration), was able to pass from the cornea to the aqueous humour after about 15 to 30 minutes.
It is believed that NAC is deacetylated (loses its acetyl group) and transforms into carnosine, which then acts as an antioxidant and against gycation.
In another study NAC was reported as effective in improving vision in cataract patients and reduced the appearance of cataract. The authors called this ‘a snow melting effect’ referring to the slow reduction of the cataractous tissues in the lens following the use of NAC eye drops. Transparency of the lens improved after using NAC eye drops at a concentration of 1% twice a day for four months. These results were relevant to all forms of cataract, mild or severe, although other studies found the most beneficial effect was in relation to early forms of cataract.
Two drops twice a day in one eye meaning 2 bottles (1 box) will last a month
Two drops twice a day in two eyes meaning 2 bottles (1 box) will last about 2 and a half weeks.
Senile cataracts are an on-going aging disorder so N-acetylcarnosine may be required on a regular basis to help maintain the eye's natural anti-oxidant defences, so a maintenance dose of 1 drop twice a day in both eyes is highly recommended and one box would last a month.
Boldyrev A, Abe H (February 1999). Cell. Mol. Neurobiol. 19 (1): 163–75. PMID 10079975.