One of the most deleterious effects of ''normal'' aging is impaired glucose metabolism. Failure to control excess sugar can trigger a cascade of ill health effects throughout the body. For example, patients with high blood sugar can suffer after-meal endothelial dysfunction, induced by a flood of glucose, fats, and abnormal proteins called advanced glycation end products entering the bloodstream.

A fat-soluble form of vitamin B1 (thiamine), may help your body to support healthy blood sugar metabolism. It acts through several mechanisms to seemingly block the biochemical pathways by which high blood sugar wreaks havoc throughout the body. In a study published in the journal Diabetes Care, scientists demonstrated for the first time that B1 (Thiamine) effectively reduced postprandial endothelial dysfunction and oxidative stress normally seen in patients with high blood sugar who were fed a heat-processed meal with a high content of advanced glycation end products. 

B1 supports normal  energy-yielding  metabolism, normal  cardiac  function and normal function  of  the  nervous  system.



References:

http://www.ncbi.nlm.nih.gov/pubmed/24643695 http://www.ncbi.nlm.nih.gov/pubmed/24399744 http://www.ncbi.nlm.nih.gov/pubmed/23091724 Nat Med. 2003 Mar;9(3):294-9. Diabetes Care 2006;29:2064-71.