Best Before End October 2026
Life Extension SAM-e provides 200mg of S-adenosyl-L-methionine per tablet, a compound your body naturally makes from the amino acid methionine. SAM-e is delicate and sensitive to light, heat and moisture, so each tablet is enteric-coated to protect it and give you a consistent dose. From Life Extension, a trusted US supplement brand since 1980.
Original price was: £24.96.£18.72Current price is: £18.72.-25%
In stock
SAM-e (S-Adenosyl-Methionine) is a naturally occurring compound in the body and is widely studied for its role in many important biological processes.
SAM-e is formed in the body from the amino acid methionine together with ATP, a molecule involved in cellular energy processes. It participates in a range of normal metabolic reactions and is also produced in supplement form using carefully controlled methods to ensure a consistent, standardised ingredient suitable for daily use.
Because SAM-e is sensitive to light, heat and moisture, it requires specific handling to maintain stability throughout its shelf life. For this reason, this product uses a protective tablet coating system together with carefully selected supporting ingredients, included to help maintain stability, tablet integrity and consistent dosing.
Each tablet provides 200 mg of S-Adenosyl-Methionine in a precisely measured format. This formulation is designed for those looking for a reliable, standardised SAM-e supplement to include as part of a regular nutritional routine.
Standardised SAM-e Dose
Provides 200mg of S-Adenosyl-Methionine per tablet.
Fermentation Derived Ingredient
Produced via a controlled fermentation process for consistency and purity.
Stabilised Tablet Format
Made with a protective coating to maintain stability and shelf life.
Suitable for Daily Use
Formulated for regular supplementation as part of a balanced routine.
Daily Intake
Take one tablet, one to three times daily, or as directed by your healthcare professional. For best use, pair with vitamins B12, B6 and folic acid.
When to take
For best results, take on an empty stomach.
Important
Do not exceed the recommended intake. SAM-e should not be taken by those diagnosed with bipolar disorder. If you are pregnant, breastfeeding, taking medication or under medical supervision, please consult a doctor or qualified health professional before use. Food supplements are not to be used as a substitute for a varied, balanced diet and healthy lifestyle. Suitable for vegetarians and vegans.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children. For best before date & batch number please see label.
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl-Methionine | 200mg | Â |
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Life Extension® SAM-e is a standardised tablet providing a single active ingredient in a carefully stabilised format.
A closer look at the key ingredients:
S-Adenosyl-Methionine (SAM-e), 200mg: a compound that occurs naturally in the body, produced through a controlled fermentation process and supplied in a standardised daily dose.
Protective tablet coating and supporting ingredients: included to help protect the SAM-e from light, heat and moisture and maintain stability throughout the product’s shelf life.
(For the full formulation, see the Ingredients tab above.)

SAM-e (S-Adenosyl-Methionine) is a compound that occurs naturally in the body and is formed from the amino acid methionine together with ATP, a molecule involved in cellular energy processes.
This supplement provides a standardised 200mg dose of SAM-e produced through controlled fermentation methods. Because SAM-e is sensitive to light, heat and moisture, the formulation uses a protective coating system and carefully selected supporting ingredients to help maintain stability and consistent dosing throughout its shelf life.
The result is a convenient, standardised tablet designed for regular daily supplementation.